It’s the same difference as the one between “dnf upgrade” and “dnf distro-sync”.
Using the latter never hurts. Especially when using cooker or rolling (where major updates happen and where we occasionally do stuff like removing epochs to clean up, resulting in a package that is newer but seems older to rpm), use distro-sync/dup.
Most of the time there won’t be any difference, especially not on rock/release.
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