Any known drawbacks to GPT vs MBR for HD > 2.0 TiB?


Lx 2014
Lx 3.03


Any experience to relate on this? Is there any drawback to GPT system?


Yes to the first and none that I know of or have heard of to the second question.

No personal experience with huge disks but according to the docs, MBR cannot fully exploit drives > 2TiB
So, in such case, GPT is mandatory.
Now, I use GPT for several years now with no problem at all.